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etravirine will lower the level or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.apalutamide will decrease the extent or outcome of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Keep away from or Use Alternate Drug. Coadministration of apalutamide, a solid CYP2C19 inducer, with medic